Mercury rules 11th and 2nd house is in 12th house in Cancer
As a Jyotish astrologer, I would interpret Mercury in the 12th house in Cancer sign as follows:
The 12th house represents isolation, secrets, and spirituality. Cancer is a water sign, ruled by the Moon, and it generally signifies emotions, mother, and family.
Mercury represents communication, intellect, and analytical skills. It is the planet of logic and reasoning.
When Mercury is placed in the 12th house in Cancer sign, it indicates that the native may have a very imaginative and sensitive mind. They may prefer seclusion and solitude, as the 12th house also relates to confinement and seclusion.
These individuals may possess a very analytical mind and prefer to work in the fields of research or analysis. They may have a great interest in understanding the unknown and the mysteries of the universe.
On the negative side, they can be fearful, anxious, and overthink things to the point of obsession. They may also struggle with finding their voice or expressing themselves. It can be challenging for them to communicate their thoughts and feelings clearly and confidently.
Overall, the placement of Mercury in the 12th house in Cancer sign indicates that the individual may have a complex and deep-rooted mental makeup, but they may find it challenging to communicate and express it openly to others.