Having Ketu in the 12th house in Leo sign can denote a unique situation for a person. This placement can cause one to feel detached from worldly desires and may result in a strong spiritual inclination. They may also experience vivid dreams and have a strong intuition. 

The native may have a tendency to spend money on charity or for the well-being of others. They may also refrain from indulging in activities that are not ethical or moral. However, they may also face difficulty in accumulating wealth and often search for spiritual fulfillment.

This placement can also lead to a strong interest in mystical and occult sciences. The native may be drawn towards meditation and seek knowledge about spirituality from gurus or teachers. They may also have trouble sleeping and may have unusual sleeping patterns.

In relationships, this placement can make it difficult for the native to trust others and may cause them to detach themselves emotionally. They may need to learn to overcome their fears and connect with others at a deeper level. 

Overall, Ketu in the 12th house in Leo sign can bring about a unique set of challenges and opportunities for the native. It is important to focus on spiritual growth and strive towards inner peace and enlightenment.

Ketu is in 12th house in Leo